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Disorders or diseases caused by deficiency or over secretion of various hormones


Hormones Causes disorder/disease Symptoms

Growth hormone (hormone of anterior pituitary gland)

Deficiency in children Drawfism Stops growth of long bone

Prematuration of body

Dwarf appearance

Over secretion in teen age Gigantism Elongation of long bones

Results in giants appearance

Over secretion in adults after adolescence Acromegaly Enlargement of body parts

Gorilla like appearance

Vasopressin or ADH (hormone of posterior pituitary gland)  

Deficiency of ADH

 

Diabetes insipidus

Large quantity of hypotonic urine

No glucose in urine

 

 

 

 

 

 

 

 

 

 

Thyroid hormone (thyroxine)

Deficiency in children Cretinism Potbellied, pigeon chested children with physical and mental retardation

Growth retardation

 

Deficiency in adults Myxedema Puffiness of skin; mental retardation,

Low body temperature, low blood pressure, low BMR

 

Deficiency of iodine in diet results in deficiency of thyroxine

 

 

Simple goiter

Swelling in thyroid gland results in swelling of neck region

Low BMR, low Blood pressure, low heart rate

Fatigue, sluggishness

 

 

 

Over secretion of thyroid hormone

 

 

Exophthalmic goiter or Grave's disease

Goiter

Bulging of eyes

Increased BMR

Increase Blood pressure and heart rate

Restlessness and nervousness

 

 

Parathormone (hormone of parathyroid gland)

 

 

Deficiency

 

 

Parathyroid tetany

 

 

Muscle spasms

Sustained contraction of muscles may lead to death

 

Over secretion Osteoporosis Decalcification of bones

Bones become soft and porous

 

 

 

 

 

 

 

Cortisol (Hormones of adrenal cortex)

 

Deficiency of both gluco and mineralocorticoids

 

Addison's disease

 

Bronze color pigmentation of skin

Low Na+ and high K+ level in blood plasma

Decrease immunity

 

Over secretion of cortisol Cushing's syndrome Abnormal obesity

High Na+ and low K+ in blood plasma

Over secretion of aldosterone Aldosteronism High Na+ and Low K+ in blood

High blood pressure, increase blood volume

Over secretion of sex corticoids Adrenal virilism Male type secondary sexual characters such as beard, moustaches and hoarse voice in female
 

 

Insulin (hormone of pancreas)

 

 

Deficiency

 

 

Diabetes mellitus

 

 

Increased blood sugar level

Excretion of glucose in urine

Increase urine volume

Increase thirst

 

Testosterone (hormone secreted by gonad) Deficiency or failure of secretion Eunuchoidism Underdevelopment of secondary sexual characters in male